Metabolite assemblies: A surprising extension to the amyloid hypothesis
Abstract
The realization of the ability of metabolites to form self-assembled amyloid-like nanostructures was a surprising phenomenon. This discovery paved the way towards understanding the pathophysiology of the inborn error of metabolism disorders from a new perspective, relating them to amyloid-associated diseases that are characterized by the aggregation of proteins and polypeptides. Hence, a 'generic amyloid hypothesis' can be proposed. This theory...
Paper Details
Title
Metabolite assemblies: A surprising extension to the amyloid hypothesis
Published Date
Oct 1, 2021
Volume
64
Pages
154 - 164
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