Clinical Importance of Left Atrial Infiltration in Cardiac Transthyretin Amyloidosis

The aim of this study was to characterize left atrial (LA) pathology in explanted hearts with transthyretin amyloid cardiomyopathy (ATTR-CM); LA mechanics using echocardiographic speckle-tracking in a large cohort of patients with ATTR-CM; and to study the association with mortality.The clinical significance of LA involvement in ATTR-CM is of great clinical interest.Congo red staining and immunohistochemistry was performed to assess the...