Astragaloside IV prevents endothelial dysfunction by improving oxidative stress in streptozotocin‑induced diabetic mouse aortas

Oxidative stress serves a role in endothelial dysfunction exhibited by patients with diabetes mellitus. Astragaloside IV (AS‑IV) is a major active ingredient of Radix Astragali, which is considered to exhibit vasoprotective effects through unknown mechanisms. Thus, the current study was performed to investigate the protective effects of AS‑IV in streptozotocin (STZ)‑induced endothelial dysfunction and to explore whether antioxidant mechanisms...