The non-coding genome in genetic brain disorders: new targets for therapy?
Abstract
The non-coding genome, consisting of more than 98% of all genetic information in humans and once judged as ‘Junk DNA’, is increasingly moving into the spotlight in the field of human genetics. Non-coding regulatory elements (NCREs) are crucial to ensure correct spatio-temporal gene expression. Technological advancements have allowed to identify NCREs on a large scale, and mechanistic studies have helped to understand the biological mechanisms...
Paper Details
Title
The non-coding genome in genetic brain disorders: new targets for therapy?
Published Date
Oct 1, 2021
Journal
Volume
65
Issue
4
Pages
671 - 683
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