Chemical and biological characterization of sulfated chitosan oligomer as heparin mimics

In the present study, chitosan oligomer was modified to sulfated chitosan oligomer (ShCsO) to mimic heparin. Its chemical structure was determined by infrared spectroscopy (FT-IR), X-ray diffractometry (XRD), differential scanning calorimetry (DSC), and thermogravimetric analysis. The results showed that the FT-IR spectrum band at 799 cm −1 corresponds to C–O–S and that at 1212 cm −1 corresponds to S=O bond stretching, which prove that the...