Association of serum KL-6 levels on COVID-19 severity: A cross-sectional study design with purposive sampling

The main target of SARS-CoV2 is the alveolar type II (AT2) cells of the lung. SARS-CoV2 evades the innate immune system resulting in the release of proinflammatory cytokines (IL-1β, IL-6, TNF-α) which causes AT2 cell damage. Krebs von den Lungen (KL-6) is a specific biomarker of AT2 cell damage. KL-6 is produced in AT2 cells that are injured/regenerated.Research that discusses the role of KL-6 in COVID-19 is still being debated and not much has...