Drinking water disinfection byproducts and ingested nitrate with the risk of endometrial cancer in postmenopausal women

BACKGROUND AND AIM: Disinfection by-products (DBPs) and {N}-nitroso compounds, formed endogenously after nitrate/nitrite ingestion, are suspected endometrial carcinogens but epidemiologic studies are limited. We investigated their relationship with endometrial cancer risk in a large prospective cohort. METHODS: Among postmenopausal women in the Iowa Women’s Health Study cohort, we evaluated ingestion of total trihalomethanes (TTHM), the sum of...