Experimental animal models of drug-induced sensorineural hearing loss: a narrative review

Objective: This narrative review describes experimental animal models of sensorineural hearing loss (SNHL) caused by ototoxic agents. Background: SNHL primarily results from damage to the sensory organ within the inner ear or the vestibulocochlear nerve (cranial nerve VIII). The main etiology of SNHL includes genetic diseases, presbycusis, ototoxic agents, infection, and noise exposure. Animal models with functional and anatomic damage to the...