CCR2 as a Marker of Carotid Plaque Disease Severity

It continues to be debated whether patients with asymptomatic carotid artery stenosis (ACAS) benefit from carotid endarterectomy (CEA). It is unknown which patients with ACAS have more vulnerable carotid plaques and can have symptomatic progression leading to stroke. Previous studies have demonstrated that a hallmark of plaque vulnerability is increased populations of inflammatory cells such as monocytes and macrophages expressing chemokine (C-C...