Comparison of the efficacy of topical insulin with autologous serum eye drops in persistent epithelial defects of the cornea

To investigate the effect of topical insulin on epithelization in persistent epithelial defects (PED) refractory to usual treatment compared to autologous serum.Retrospective, consecutive case-control series.The charts of 61 consecutive patients with PED treated with topical insulin (case group) and 23 treated with autologous serum (control group) were reviewed. Primary efficacy end points were the percentage of patients in which epithelization...