Molecular dynamics simulation to explore the synergistic inhibition effect of kinetic and thermodynamic hydrate inhibitors

The combined injection of kinetic and thermodynamic hydrate inhibitors (KHIs and THIs) is considered as a promising method to prevent the blockage of oil and gas pipelines caused by the accidental formation of methane hydrate. To develop better strategies for enhancing inhibition effects, molecular dynamics simulation is employed to investigate the synergistic mechanism of a KHI and a THI (PVP-A and methanol, respectively). Our results show that...