Assessing disease activity using the pediatric Crohn’s disease activity index: Can we use subjective or objective parameters alone?

BACKGROUND The pediatric Crohn's disease activity index (PCDAI) is used as a standard tool to assess disease activity in clinical trials for pediatric Crohn's disease. AIM To examine which items on the PCDAI drive assessment of disease activity, and how subgroups of subjective and objective items reflect change in disease state over time. METHODS Selective raw data from three prospectively collected datasets were combined, including 703 children...