Global fractional anisotropy predicts transition to psychosis after 12 months in individuals at ultra‐high risk for psychosis

Psychosis spectrum disorders are associated with cerebral changes, but the prognostic value and clinical utility of these findings are unclear. Here, we applied a multivariate statistical model to examine the predictive accuracy of global white matter fractional anisotropy (FA) for transition to psychosis in individuals at ultra-high risk for psychosis (UHR).110 UHR individuals underwent 3 Tesla diffusion-weighted imaging and clinical...