Hirsutism and Menstrual Irregularity in a 16-year-old Girl

A 16-year-old girl presents to the clinic for follow-up of polycystic ovarian syndrome (PCOS) and type 2 diabetes. She was diagnosed as having PCOS and type 2 diabetes 3 years ago; laboratory studies at that time included the following results (reference ranges): hemoglobin A1c, 6.7%; total testosterone, 53 ng/dL (1.87 nmol/L) (6–50 ng/dL [0.21–1.74 nmol/L]); free testosterone, 14.5 pg/mL (50.32 pmol/L) (0.9–6.8 pg/mL [3.12–23.60 pmol/L]);...