Original paper
Insulin-like growth factor-1 directly affects cardiac cellular remodelling via distinct pathways
Abstract
Studies of insulin-like growth factor 1 (IGF-1) as a novel therapy for the treatment of cardiovascular diseases have proven promising. However, elevated IGF-1 levels have also been associated with poor patient outcomes in heart failure with reduced ejection fraction. IGF-1 therapy has additionally been shown to not be beneficial in the percutaneous coronary intervention setting. Although IGF-1 activation of the PI3K/Akt and ERK1/2 pathways have...
Paper Details
Title
Insulin-like growth factor-1 directly affects cardiac cellular remodelling via distinct pathways
Published Date
Oct 1, 2021
Journal
Volume
36
Pages
100852 - 100852
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Notes
History