Iron parameters in patients with partial lipodystrophy and impact of exogenous leptin therapy

Provocative rodent studies taken together with cross-sectional human epidemiological data have shown that there may be a cross-talk between circulating leptin levels and whole-body iron metabolism.1 2 In this study, we aim to discover the effects of recombinant leptin administration on iron parameters in patients with partial lipodystrophy. We studied serum samples from 19 patients with partial lipodystrophy (median age: 42 years, IQR: 34–57,...