Review paper
Can polarization of macrophage metabolism enhance cardiac regeneration?
Abstract
While largely appreciated for their antimicrobial and repair functions, macrophages have emerged as indispensable for the development, homeostasis, and regeneration of tissue, including regeneration of the neonatal heart. Upon activation, mammalian neonatal macrophages express and secrete factors that coordinate angiogenesis, resolution of inflammation, and ultimately cardiomyocyte proliferation. This is contrary to adult macrophages in the...
Paper Details
Title
Can polarization of macrophage metabolism enhance cardiac regeneration?
Published Date
Nov 1, 2021
Volume
160
Pages
87 - 96
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