Induced proximity tools for precise manipulation of lipid signaling
Abstract
Lipids are highly dynamic molecules that, due to their hydrophobicity, are spatially confined to membrane environments. From these locations, certain privileged lipids serve as signaling molecules. For understanding the biological functions of subcellular pools of signaling lipids, induced proximity tools have been invaluable. These methods involve controlled heterodimerization, by either small-molecule or light triggers, of functional proteins....
Paper Details
Title
Induced proximity tools for precise manipulation of lipid signaling
Published Date
Dec 1, 2021
Volume
65
Pages
93 - 100
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