Photon, proton, neutron and alpha shielding features of 10TiO 2 –10SiO 2 -(80-x)B 2 O 3 -xBaO were studied. This study exhibits several photon shielding parameters such as mass attenuation coefficient (MAC), half-value layer (HVL), effective atomic number ( Z eff ), effective electron density (N eff ), gamma dose rate (R/h), specific gamma-ray constant (Γ), and the specific absorbed fraction of the energy (SAFE). The effective removal cross-section of the fast neutron (Σ R ), scattering length of the constituent elements, mass stopping power (MSP), and projected range variation parameters were used to explore the particle shielding features. Moreover, the MAC was determined by using Geant4 simulation and compared with the results of the Phy-X program. The percentage error (Δ) was less than 2% for all results, which revealed the agreement between Geant4 simulation and Phy-X program. Although, the addendum of barium oxide (BaO) led to improving the performance of MAC, HVL, Z eff , N eff , and Γ. The Σ R , MSP and projected range variation showed a progressive reduction with incorporation BaO. Lastly, the BaO and SiO 2 played an amazing role in enhancement the durability for the glass sample, and the S4 sample exhibits the highest durability compared with other samples. From the obtained results, it can be concluded that the present glass samples can be used in the radiation-shielding field. • A series of borosilicate glass samples was prepared by the ordinary melt quench method. • The prepared samples appeared attractive results in the radiation shielding field. • Photon, neutron, and proton shielding properties were investigated.