Quantifying myelin in crossing fibers using diffusion‐prepared phase imaging: Theory and simulations

Purpose Myelin has long been the target of neuroimaging research. However, most available techniques can only provide a voxel‐averaged estimate of myelin content. In the human brain, white matter fiber pathways connecting different brain areas and carrying different functions often cross each other in the same voxel. A measure that can differentiate the degree of myelination of crossing fibers would provide a more specific marker of myelination....