The dynamic broad epigenetic (H3K4me3, H3K27ac) domain as a mark of essential genes

Volume: 13, Issue: 1
Published: Jul 8, 2021
Abstract
Transcriptionally active chromatin is marked by tri-methylation of histone H3 at lysine 4 (H3K4me3) located after first exons and around transcription start sites. This epigenetic mark is typically restricted to narrow regions at the 5`end of the gene body, though a small subset of genes have a broad H3K4me3 domain which extensively covers the coding region. Although most studies focus on the H3K4me3 mark, the broad H3K4me3 domain is associated...
Paper Details
Title
The dynamic broad epigenetic (H3K4me3, H3K27ac) domain as a mark of essential genes
Published Date
Jul 8, 2021
Volume
13
Issue
1
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