Internal medicine

Lymphocyte

Disease

Coronavirus disease 2019 (COVID-19)

Infectious disease (medical specialty)

Gastroenterology

Interleukin 6

Odds ratio

Mean platelet volume

Immunology

Inflammation

Coronavirus

C-reactive protein

Neutrophil to lymphocyte ratio

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Medicine

Platelet

Revista da Associação Médica Brasileira

Can the neutrophil/lymphocyte ratio (NLR) have a role in the diagnosis of coronavirus 2019 disease (COVID-19)? by Nalbant et al. 1 , which was published in your journal's May 2020 issue.Neutrophil/lymphocyte ratio (NLR), Platelet /lymphocyte ratio (PLR), and c-reactive protein (CRP), three important inflammatory markers, were found to be higher in Covid-19 positive patients than Covid-19 negative subjects 1 .CRP is a universal inflammatory marker and increases in many infectious and inflammatory conditions.Despite that the correlation between NLR and CRP or PLR and CRP was not evaluated in the study, the authors found that an NLR level greater than 2.4% has an odds ratio of 20.3 for positive Covid-19 test result 1 .Hemogram indexes are considered novel inflammatory markers in many recent studies in the literature.Of these, elevated NLR is suggested as a predictor of poor outcome in patients with Covid-19 infection 2,3 .Covid-19 patients with high NLR levels were reported to have increased interleukin-6 and tumor necrosis factor-alpha and appeared to recover more difficultly than those with lower NLR levels 4 .Mean platelet volume (MPV) is another inflammatory marker derived from the hemogram test.Despite MPV values of Covid-19 positive and negative subjects were not 1

Hematological predictors of novel Coronavirus infection