Review paper
Direct visualization and profiling of protein misfolding and aggregation in live cells
Abstract
Over the past few years, research tools have been developed to monitor the multistep protein aggregation process in live cells, a process that has been associated with a growing number of human diseases. Herein, we describe recent advances in methods that can either survey the distribution of aggregation at the level of the cellular proteome using mass spectroscopy or discern the multistep aggregation process of specific proteins of interest via...
Paper Details
Title
Direct visualization and profiling of protein misfolding and aggregation in live cells
Published Date
Oct 1, 2021
Volume
64
Pages
116 - 123
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