Novel impedance‐pH parameters are associated with proton pump inhibitor response in patients with inconclusive diagnosis of gastro‐oesophageal reflux disease according to Lyon Consensus

Summary Background The Lyon Consensus delineates impedance‐pH parameters that can demonstrate/exclude gastro‐oesophageal reflux disease (GERD). In patients with acid exposure time between 4% and 6%, GERD diagnosis has been considered inconclusive. In these cases, mean nocturnal baseline impedance (MNBI) and post‐reflux swallow‐induced peristaltic wave (PSPW) index may either confirm or refute GERD diagnosis and represent predictors of proton...