Monogenic and Polygenic Models of Coronary Artery Disease
Abstract
Coronary artery disease (CAD) is a common disease globally attributable to the interplay of complex genetic and lifestyle factors. Here, we review how genomic sequencing advances have broadened the fundamental understanding of the monogenic and polygenic contributions to CAD and how these insights can be utilized, in part by creating polygenic risk estimates, for improved disease risk stratification at the individual patient level. Initial...
Paper Details
Title
Monogenic and Polygenic Models of Coronary Artery Disease
Published Date
Jul 1, 2021
Journal
Volume
23
Issue
8
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