Original paper
PD‐1‐induced proliferating T cells exhibit a distinct transcriptional signature
Abstract
Summary Ligation of the inhibitory receptor PD‐1 on T cells results in the inhibition of numerous cellular functions. Despite the overtly inhibitory outcome of PD‐1 signalling, there are additionally a collection of functions that are activated. We have observed that CD4 + T cells stimulated through the T‐cell receptor and PD‐1 primarily do not proliferate; however, there is a population of cells that proliferates more than T‐cell receptor...
Paper Details
Title
PD‐1‐induced proliferating T cells exhibit a distinct transcriptional signature
Published Date
Jul 12, 2021
Journal
Volume
164
Issue
3
Pages
555 - 568
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Notes
History