Prolonged parent-child separation and pain in adolescence: The role of HPA-axis genetic variations

Increasing evidence has demonstrated that childhood adversity was a predictor of pain and hypothalamic-pituitary-adrenal (HPA) axis genetic variation is associated with pain risk. This study aims to explore possible effects of prolonged childhood separation from parents and HPA polygenic risk score (PRS) on pain among adolescents in rural China.We used data from 219 adolescents in rural area of Fuyang city, Anhui province, China. Parent-child...