Level of maternal respiratory syncytial virus (RSV) F antibodies in hospitalized children and correlates of protection

BackgroundRespiratory syncytial virus (RSV) is a major cause of lower respiratory infection among children and no vaccine is available. The stabilized form of the fusion (F) protein – pre-F – is a leading vaccine candidate to target different populations, including pregnant women. This study aimed to determine the magnitude and nature of RSV-directed maternal antibodies (matAbs) in hospitalized children with RSV infection.MethodsSixty-five...