Internal medicine

Pathology

Organic chemistry

Ethylenediaminetetraacetic acid

Disease

Pathophysiology

Endocrinology

Neurofilament

Whole blood

Immunohistochemistry

Chemistry

Chelation

Amyloid (mycology)

Neurodegeneration

Tau protein

Glial fibrillary acidic protein

Alzheimer's disease

Medicine

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring

We tested how tube types (ethylenediaminetetraacetic acid [EDTA], serum, lithium heparin [LiHep], and citrate) and freeze-thaw cycles affect levels of blood biomarkers for Alzheimer's disease (AD) pathophysiology, glial activation, and neuronal injury.

Effects of pre‐analytical procedures on blood biomarkers for Alzheimer's pathophysiology, glial activation, and neurodegeneration