Radiographical assessment of tumour stroma and treatment outcomes using deep learning: a retrospective, multicohort study

BackgroundThe tumour stroma microenvironment plays an important part in disease progression and its composition can influence treatment response and outcomes. Histological evaluation of tumour stroma is limited by access to tissue, spatial heterogeneity, and temporal evolution. We aimed to develop a radiological signature for non-invasive assessment of tumour stroma and treatment outcomes.MethodsIn this multicentre, retrospective study, we...