Angelica sinensis extract promotes neuronal survival by enhancing p38 MAPK–mediated hippocampal neurogenesis and dendritic growth in the chronic phase of transient global cerebral ischemia in rats

Angelica sinensis (Oliv.) Diels (ASD), commonly known as Dang Gui, is a popular Chinese herb that has long been used to treat ischemic stroke. However, the effects of ASD in chronic cerebral ischemia and its underlying mechanisms still remain unclear.This study aimed to determine the effects of the ASD extract on hippocampal neuronal survival at 28 d after transient global cerebral ischemia (GCI) and to investigate the precise mechanisms...