CGRP receptor antagonists for migraine. Are they also AMY 1 receptor antagonists?
Abstract
The development of several drugs that target the calcitonin gene-related peptide (CGRP) system has been a major breakthrough in the pharmacological management of migraine. These are divided into two major classes, antibodies which bind to the CGRP peptide, preventing it from activating CGRP receptors and receptor antagonists. Within the receptor antagonist class, there are two mechanisms of action, small molecule receptor antagonists and an...
Paper Details
Title
CGRP receptor antagonists for migraine. Are they also AMY 1 receptor antagonists?
Published Date
Jun 24, 2021
Volume
179
Issue
3
Pages
454 - 459
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