Characterization of structural variation in Tibetans reveals new evidence of high-altitude adaptation and introgression
Abstract
Background Structural variation (SV) acts as an essential mutational force shaping the evolution and function of the human genome. However, few studies have examined the role of SVs in high-altitude adaptation and little is known of adaptive introgressed SVs in Tibetans so far. Results Here, we generate a comprehensive catalog of SVs in a Chinese Tibetan (n = 15) and Han (n = 10) population using nanopore sequencing technology. Among a total of...
Paper Details
Title
Characterization of structural variation in Tibetans reveals new evidence of high-altitude adaptation and introgression
Published Date
May 25, 2021
Journal
Volume
22
Issue
1
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