Industry updates from the field of stem cell research and regenerative medicine in April 2021.

Published on Jun 2, 2021in Regenerative Medicine2.598
· DOI :10.2217/RME-2021-0065
Dusko Ilic49
Estimated H-index: 49
('KCL': King's College London),
Mirjana Liovic13
Estimated H-index: 13
(University of Ljubljana)
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Abstract
Latest developments in the field of stem cell research and regenerative medicine compiled from publicly available information and press releases from nonacademic institutions in April 2021.
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#1Marie-Catherine Giarratana (University of Paris)H-Index: 2
#2Ladan Kobari (University of Paris)H-Index: 3
Last. Luc Douay (University of Paris)H-Index: 37
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We describe here the large-scale ex vivo production of mature human red blood cells (RBCs) from hematopoietic stem cells of diverse origins. By mimicking the marrow microenvironment through the application of cytokines and coculture on stromal cells, we coupled substantial amplification of CD34+ stem cells (up to 1.95 × 106-fold) with 100% terminal differentiation into fully mature, functional RBCs. These cells survived in nonobese diabetic/severe combined immunodeficient mice, as do native RBCs...
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