Original paper

Pembrolizumab alone or combined with chemotherapy versus chemotherapy as first-line therapy for advanced urothelial carcinoma (KEYNOTE-361): a randomised, open-label, phase 3 trial

Volume: 22, Issue: 7, Pages: 931 - 945
Published: Jul 1, 2021
Abstract
PD-1 and PD-L1 inhibitors are active in metastatic urothelial carcinoma, but positive randomised data supporting their use as a first-line treatment are lacking. In this study we assessed outcomes with first-line pembrolizumab alone or combined with chemotherapy versus chemotherapy for patients with previously untreated advanced urothelial carcinoma.KEYNOTE-361 is a randomised, open-label, phase 3 trial of patients aged at least 18 years, with...
Paper Details
Title
Pembrolizumab alone or combined with chemotherapy versus chemotherapy as first-line therapy for advanced urothelial carcinoma (KEYNOTE-361): a randomised, open-label, phase 3 trial
Published Date
Jul 1, 2021
Volume
22
Issue
7
Pages
931 - 945
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