Review paper
Epigenetic memory in reprogramming
Abstract
A central question of biology is the basis of stable cell fates. Cell fates are formed during development, where the zygote progresses from totipotency to terminal differentiation. Each step of lineage commitment involves establishment of stable states encoding-specific developmental commitments that can be faithfully transmitted to daughter cells - a 'memory' of cell fate is acquired. However, this cell-fate memory is reversible and can be...
Paper Details
Title
Epigenetic memory in reprogramming
Published Date
Oct 1, 2021
Volume
70
Pages
24 - 31
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History