Original paper
Single-cell manifold-preserving feature selection for detecting rare cell populations
Abstract
A key challenge in studying organisms and diseases is to detect rare molecular programs and rare cell populations that drive development, differentiation and transformation. Molecular features, such as genes and proteins, defining rare cell populations are often unknown and are difficult to detect from unenriched single-cell data using conventional dimensionality reduction and clustering-based approaches. Here, we propose an unsupervised...
Paper Details
Title
Single-cell manifold-preserving feature selection for detecting rare cell populations
Published Date
May 20, 2021
Journal
Volume
1
Issue
5
Pages
374 - 384
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Notes
History