Low-cost CRISPR diagnostics for resource-limited settings

Next-generation sequencing (NGS) has identified disease hallmarks and catalogued a vast reservoir of genetic information from humans and other species. Precise nucleotide-interrogation properties of clustered regularly interspaced short palindromic repeats (CRISPR) proteins have been harnessed to rapidly identify DNA–RNA signatures for diverse applications, bypassing the cost and turnaround times associated with diagnostic NGS. Next-generation...