Nonhuman glycans can regulate anti–factor VIII antibody formation in mice
Abstract
Recombinant factor VIII (FVIII) products represent a life-saving intervention for patients with hemophilia A. However, patients can develop antibodies against FVIII that prevent its function and directly increase morbidity and mortality. The development of anti-FVIII antibodies varies depending on the type of recombinant product used, with previous studies suggesting that second-generation baby hamster kidney (BHK)-derived FVIII products display...
Paper Details
Title
Nonhuman glycans can regulate anti–factor VIII antibody formation in mice
Published Date
Mar 3, 2022
Journal
Volume
139
Issue
9
Pages
1312 - 1317
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