Disruption of endoplasmic reticulum homeostasis exacerbates liver injury in clinically ketotic cows
Abstract
Disruption of endoplasmic reticulum (ER) homeostasis, a condition termed “ER stress,” contributes to the development of liver injury in nonruminants. Because liver injury is a prominent pathological feature associated with overproduction of ketone bodies in dairy cows with ketosis, understanding the ER stress state and its functional consequences on liver injury is of particular interest. Here, 30 multiparous cows (within 3 wk postpartum)...
Paper Details
Title
Disruption of endoplasmic reticulum homeostasis exacerbates liver injury in clinically ketotic cows
Published Date
Aug 1, 2021
Journal
Volume
104
Issue
8
Pages
9130 - 9141
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