Original paper
Conotoxin loaded dextran microgel particles alleviate effects of spinal cord injury by inhibiting neuronal excitotoxicity
Abstract
Spinal cord injury (SCI) is a severe refractory disabling condition accompanied by complicated pathological processes, such as excessive glutamate release in the extracellular environment and massive influx of Ca2+ into cells. Dextran can absorb extracellular glutamate and Ca2+ to attenuate persistent excitatory processes that are detrimental to normal cells. Calcium channel inhibitors reduce the influx of Ca2+, thereby relieving subsequent...
Paper Details
Title
Conotoxin loaded dextran microgel particles alleviate effects of spinal cord injury by inhibiting neuronal excitotoxicity
Published Date
Jun 1, 2021
Journal
Volume
23
Pages
101064 - 101064
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Notes
History