Atrial coupling-index by standard echocardiography in degenerative mitral regurgitation: An incremental determinant of survival

We ought to determine the prognostic role of left atrial coupling-index (LACI), as left atrial volume-index (LAVI) by tissue-Doppler-Imaging a′ (TDI-a′), in a large cohort of degenerative mitral regurgitation (DMR). All consecutive 4792 patients (61 ± 16 years, 48% women) with isolated DMR diagnosed at the Mayo Clinic 2003–2011, comprehensively characterized, in whom LAVI and TDI-a’ in sinus rhythm was prospectively measured in routine practice,...