Review paper
Near infrared photoimmunotherapy of cancer; possible clinical applications
Abstract
Near-infrared photoimmunotherapy (NIR-PIT) is a new cancer treatment that uses an antibody-photo-absorber conjugate (APC) composed of a targeting monoclonal antibody conjugated with a photoactivatable phthalocyanine-derivative dye, IRDye700DX (IR700). APCs injected into the body can bind to cancer cells where they are activated by local exposure to NIR light typically delivered by a NIR laser. NIR light alters the APC chemical conformation...
Paper Details
Title
Near infrared photoimmunotherapy of cancer; possible clinical applications
Published Date
May 7, 2021
Journal
Volume
10
Issue
12
Pages
3135 - 3151
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