Coronary calcium, coronary CTA and intention to diagnose: Interpreting the uninterpretable

Calcified plaque has been the Achilles Heel of coronary computed tomography angiography (CTA) since its inception, and, unfortunately, has remained refractory to most corrective measures. It has, in part, been responsible for slowing dissemination of CTA, since referring physicians are unhappy if uninterpretable, heavily calcified lesions are reported as obstructive, when subsequent invasive coronary angiography most often reveals no obstructive...