Hypoxia/Temperature/pH Triple Stimuli–Responsive Block Copolymers: Synthesis, Self‐Assembly, and Controlled Drug Release
Abstract
The amphiphilic block copolymer poly(methacrylic acid ‐co‐ 2‐nitroimidazole acrylate) ‐b‐ poly(2‐( N , N ‐dimethylamino)ethyl methacrylate) (P(MAA ‐co‐ NIMA) ‐b‐ PDMAEMA) with the hypoxia/temperature/pH triple responsiveness is synthesized by reversible addition‐fragmentation chain transfer polymerization (RAFT), hydrolysis, and 3‐(3‐dimethylaminopropyl)‐1‐ethylcarbodiimide (EDC) reactions, and successfully self‐assembled into micelles. The...
Paper Details
Title
Hypoxia/Temperature/pH Triple Stimuli–Responsive Block Copolymers: Synthesis, Self‐Assembly, and Controlled Drug Release
Published Date
Apr 18, 2021
Volume
306
Issue
6
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