Original paper
Hyperoxidation of Peroxiredoxins and Effects on Physiology of Drosophila
Abstract
The catalytic activity of peroxiredoxins (Prx) is determined by the conserved peroxidatic cysteine (CysP), which reacts with peroxides to form sulfenic acid (Cys-SOH). Under conditions of oxidative stress, CysP is oxidized to catalytically inactive sulfinic (Cys-SO2) and sulfonic (Cys-SO3) forms. The Cys-SO2 form can be reduced in a reaction catalyzed by sulfiredoxin (Srx). To explore the physiological significance of peroxiredoxin...
Paper Details
Title
Hyperoxidation of Peroxiredoxins and Effects on Physiology of Drosophila
Published Date
Apr 15, 2021
Journal
Volume
10
Issue
4
Pages
606 - 606
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Notes
History