Accelerated degradation of poly(l-lactide) bone scaffold: Crystallinity and hydrophilicity

The too low degradation rate of poly (l-lactic acid) (PLLA) hinders its wide application as scaffold for bone tissue engineering to some extent due to high amount of crystal region, although PLLA possesses good biocompatibility, biodegradability and processibility. In this study, l-lactic (L-LA) was incorporated into PLLA bone scaffold fabricated by selective laser sintering (SLS) to promote the degradation. The mechanism was that L-LA was...