Polygenic Score Models for Alzheimer’s Disease: From Research to Clinical Applications
Abstract
The high prevalence of Alzheimer’s disease (AD) among the elderly population and its lack of effective treatments make this disease a critical threat to human health. Recent epidemiological and genetics studies have revealed the polygenic nature of the disease, which is possibly explainable by a polygenic score model that considers multiple genetic risks. Here, we systemically review the rationale and methods used to construct polygenic score...
Paper Details
Title
Polygenic Score Models for Alzheimer’s Disease: From Research to Clinical Applications
Published Date
Mar 29, 2021
Journal
Volume
15
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