Original paper
Computational epitope map of SARS-CoV-2 spike protein
Volume: 17, Issue: 4, Pages: e1008790 - e1008790
Published: Apr 1, 2021
Abstract
The primary immunological target of COVID-19 vaccines is the SARS-CoV-2 spike (S) protein. S is exposed on the viral surface and mediates viral entry into the host cell. To identify possible antibody binding sites, we performed multi-microsecond molecular dynamics simulations of a 4.1 million atom system containing a patch of viral membrane with four full-length, fully glycosylated and palmitoylated S proteins. By mapping steric accessibility,...
Paper Details
Title
Computational epitope map of SARS-CoV-2 spike protein
Published Date
Apr 1, 2021
Journal
Volume
17
Issue
4
Pages
e1008790 - e1008790