The road goes ever on: innovations and paradigm shifts in atrial fibrillation management

Symptoms suggestive of atrial fibrillation (AF) have been described for centuries, and William Harvey already noted an undulating palpitation of the right auricle in animals in 1628.1 However, it was not until 1906 that the Dutch physician and physiologist Willem Einthoven published the first electrocardiogram showing AF in a patient and it took several more years before AF was recognized as a clinical entity.2 Today, in 2021, AF remains a major...